Abstract

CALLE LOPEZ, Yamile; MONTES GAVIRIA, María Isabel  and  TORO PEREZ, María Eugenia. Restless leg syndrome (Willis-Ekbom Disease). Acta Neurol Colomb. [online]. 2016, vol.32, n.4, pp.347-356. ISSN 0120-8748.  https://doi.org/10.22379/24224022119.

Summary Restless leg syndrome (RLS) is a sensory motor disorder in which the patient referred an urge to move the limbs, which may be accompanied by an ill-defined sense, and up to 50% of cases with pain, difficult to locate, and initially manifests in the legs. It occurs mostly at night, disrupting sleep and subsequently affecting the quality of life of patients. It is classically divided into primary and secondary restless legs syndrome, based on the presence or absence of comorbidities related to the treatment and prognosis of RLS. This disease has an incidence in the general population of 9-22 patients per 1,000 people per year (equivalent to 1.7% per year); with a prevalence of 5-13% of the general population. The diagnosis of RLS is done by using the criteria established by the International RLS study group, divided into essential and supportive. The treatment's cornerstone are dopamine agonists, and other drugs, such as gabapentin enacarbil that have been used more recently. The importance of the disease lies in the negative impact it has on the quality of life of affected patients in general, and increased mortality in patients with end stage renal disease comorbidity in particular.

Keywords : rrestless legs síndrome; iron deficiency; polyneuropathies; pregnancy; sleep; treatment.

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