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Acta Neurológica Colombiana

versión impresa ISSN 0120-8748

Resumen

GIL-TAMAYO, Sebastián et al. Dietary supplements in cognitive impairment and Alzheimer's disease: a literature review. Acta Neurol Colomb. [online]. 2017, vol.33, n.1, pp.37-45. ISSN 0120-8748.  http://dx.doi.org/10.22379/24224022129.

OBJECTIVES:

To evaluate the effects of omega 3 fatty acids consumption in the form of dietary supplement, complement or food-products presentation on adult cognitive function.

METHODS:

A literature review in two databases (Medline and Embase) was undertaken, searching for clinical trials, observational studies, systematic reviews and experimental studies concerning omega-3 fatty acids and their relation with cognitive function and Alzheimer's disease.

RESULTS:

Most studies linked supplementation with omega-3 capsules and consumption of fish and other omega-3 containing foods with results in cognitive function testing, outcomes in diseases or diagnostic imaging and found beneficial effects, which seem to be stronger in healthier persons with better cognitive function at baseline. There were differences in the results found in clinical trials and systematic reviews, which could be attributable to the variability in the supplementation dose, the length of follow-up and the methods used to assess cognitive function and decline.

CONCLUSION:

The use of omega-3 fatty acids in supplement, complement or food-products presentation seems to have beneficial effects in the cognitive function of healthy adults.

Palabras clave : Alzheimer Disease; Cognition; Dietary supplements; Docosahexaenoic Acids; Eicosapentae-noic Aci; Fatty acids.(MeSH).

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