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Acta Neurológica Colombiana
Print version ISSN 0120-8748
Abstract
CASTILLO CASTELBLANCO, Gabriel Augusto; RAMIREZ GARCIA, Sergio Francisco; PENUELA NOVOA, Diana Jeannette and HERNANDEZ PRECIADO, José Fernando. Autism treatment with magnetic stimulation: neurophysiological bases. Acta Neurol Colomb. [online]. 2018, vol.34, n.1, pp.101-103. ISSN 0120-8748. https://doi.org/10.22379/24224022185.
Autism and Autism Spectrum Disorders are neurodevelopmental disorders. The critical periods of neurodevelopment end in the structural consolidation of a neuronal circuit and its connectivity. These periods are regulated by inhibitory interneurons that express the parvalbumin protein. The absence of parvalbumin in Autism leads to an imbalance of the excitation inhibition ratio. Hyperexcitability prevents adequate synchronization and connectivity with other brain regions. Transcraneal Magnetic Stimulation in Autism and ASD attempts to modify the neurophysiological abnormalities of the compromised circuits.
Keywords : Autism; Autism Spectrum Disorder; Neurodevelopmental Disorders; Neurophysiology; Transcranial Magnetic Stimulation (MeSH).