Abstract

MORENO SANCHEZ, Diego Fernando; MUNOZ, Cristian; LENIS, Luis Eduardo  and  ERNESTO NIETO, Luis. Subacute combined degeneration in a patient without anemia but with severe hypertension. Acta Neurol Colomb. [online]. 2018, vol.34, n.2, pp.123-128. ISSN 0120-8748.  https://doi.org/10.22379/24224022200.

Sub-acute combined degeneration is a neuropsychiatrical pathology associated with vitamin B12 deficiency It is clinically manifested through sensorial ataxia, peripheral neuropathy, cognitive dysfunction and optical neuropathy; these manifestations are generally attributed to the abnormal synthesis of myelin. It can have a nonspecific clinical presentation but the measurement of the levels of vitamin B12, some serum metabolites, and the use of neuroimaging methods help to confirm the diagnose when suspected. The case of a patient with sub-acute combined degeneration is described below. The patient was attended because of neurological symptoms and severe hypertension, and after the treatment, the patient's neurological and vascular symptomatology improved.

Keywords : Methylmalonic acid; Subacute combined degeneration; Homocysteine; Inflammatory Myelo-pathy; Neuroimaging; Vitamin B12 (MeSH).

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