Abstract

SAAVEDRA MORENO, Juan Sebastián; MILLAN, Paula Andrea  and  BURITICA HENAO, Omar Fredy. Introduction, epidemiology and diagnosis of Parkinson's disease. Acta Neurol Colomb. [online]. 2019, vol.35, suppl.1, pp.2-10. ISSN 0120-8748.  https://doi.org/10.22379/24224022244.

Parkinson's disease is a neurodegenerative disorder that has multiple motor and non-motor manifestations. The pathological process begins years or decades before the onset of non-motor symptoms, at which time other symptoms develop that frequently precede clinical debut. Although much progress has been made in the knowledge of pathogenesis and in the recognition of the numerous non-motor manifestations, the diagnosis is still focused on motor syndrome or parkinsonism. This chapter shows an update on recent data related to the increase in the global prevalence of the disease, as well as the diagnosis based on the new criteria defined by the Movement Disorders Society in 2015, which focus on the central criteria but defined red flags for the possible existence of other parkinsonisms, absolute exclusion criteria and support criteria, the latter recognizing the utility of non-motor symptoms and some paraclinical aids to support in vivo diagnosis.

Keywords : Parkinson's disease; Consensus; Neurodegeneration; Prevalence; Epidemiology; Diagnosis (MeSH).

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