Servicios Personalizados
Revista
Articulo
Indicadores
- Citado por SciELO
- Accesos
Links relacionados
- Citado por Google
- Similares en SciELO
- Similares en Google
Compartir
Acta Neurológica Colombiana
versión impresa ISSN 0120-8748versión On-line ISSN 2422-4022
Resumen
RAMIREZ, Sergio y AYALA-CASTILLO, Miguel Ángel. Paracoccidioidomycosis with central nervous system involvement. Acta Neurol Colomb. [online]. 2021, vol.37, n.1, suppl.1, pp.106-111. Epub 23-Mayo-2021. ISSN 0120-8748. https://doi.org/10.22379/24224022341.
Paracoccidioidomycosis (PMC) is an endemic mycosis that affects different regions of Central and South America. This disease is caused by Paracoccidioides brasiliensis and Paracoccidioides lutzii. Its clinical presentation can be acute, subacute or chronic, affecting different systems including the central nervous system. Lung and mucosal involvement are the most common. Neuroparacoccidioidomycosis (NPCM) occurs in 25 % of patients with PMC, it can be classified as meningeal or pseudotumoral form. Its neurological symptoms can present as headache or motor deficit, that depends on the location. The study of cerebrospinal fluid is nonspecific and microbiological isolation is very rare. Lesions seen on neuroimaging can be confused with other fungal infections or even tumors. Histological study confirms the diagnosis. Trimethoprim-sulfamethaxazole, amphotericin B, and fluconazole can be used for the treatment of NPCM. Some cases may require surgical management.
Palabras clave : paracoccidioidomycosis; central nervous system (MeSH).