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Acta Neurológica Colombiana
Print version ISSN 0120-8748On-line version ISSN 2422-4022
Abstract
PARRA, Angie Viviana et al. Pseudoathetosis of the upper limbs as a manifestation of vitamin B12 deficit: about a case. Acta Neurol Colomb. [online]. 2021, vol.37, n.2, pp.69-74. Epub July 05, 2021. ISSN 0120-8748. https://doi.org/10.22379/24224022369.
INTRODUCTION:
Sensory ganglionopathy is a rare complication of vitamin B12 deficiency, causing an spectrum of neurologic symptoms such as abnormal vibratory sensitivity, proprioception, gait disturbance and rarely movement disorders like pseudoatetosis and dystonia.
CLINICAL CASE:
A73-year-old man was admitted with numbness and clumsiness of his extremities, burning pain on palms and soles, postural instability and impaired walking. Neurological examination demonstrated hypesthesia and sensory ataxia of four limbs with associated pseudo athetoid movements of the upper limbs as a consequence of ganglionopathy by vitamin B12 deficiency, showing typical MRI inverted "V" sign due to degeneration of central projections from large sensory neurons, which was successfully treated with IM cyanocobalamin 4 months later.
CONCLUSIONS:
Sensory ganglionopathy in B12 deficit is a potentially reversible and underdiagnosed condition, which occasionally can present with movement disorders. Must be suspected in patiens presenting with sensory deficits depending on richly myelinated axons. Usually with good prognosis after identifying the deficit's cause and giving propper treatment.
Keywords : athetosis; dystonia; movement disorders; ataxia; peripheral nervous system; vitamin B12 deficiency (MeSH).