Abstract

CASTANO LL, Rodrigo et al. Dilatación endoscópica y aplicación de esteroides intralesionales en las estenosis esofágicas por cáusticos y posquirúrgicas. Rev Col Gastroenterol [online]. 2005, vol.20, n.2, pp.06-11. ISSN 0120-9957.

Background: Intralesional corticosteroid injection has been shown to be effective in refractory esophageal strictures of various aetiologies. The present study was conducted to determine the efficacy of intralesional triamcinolone in augmenting results of endoscopic dilation in corrosive esophageal and post surgical strictures. Methods: From 56 patients with esophageal stenosis, 35 for caustic and 21 postsurgical, 17 patients with ingest of corrosive and 11 postoperative they underwent the dilation and application of intralesional triamcinolona. The interval between dilations and frequency of dilation were calculated before and after corticosteroid injections, and periodic dilation index was calculated as number of dilations/number of months before and after dilation. Results: The mean age of the 28 patients with injection of triamcinolone (13 men and 15 women) were 36 years (range 15 to 70) and for the control group 29 years (range 15 to 68). There were no differences between control group and patients with steroids regard stricture aetiology, long, ubication and sex distribution. Ten patients received a single injection of triamcinolone, whereas 13 had two and five patients had three sessions. The entire patient was dilated before steroid application. The median periodic dilation index was calculated before and after corticosteroid therapy with significative differences in favour of postsurgical group (p<0.01). Conclusions: Intralesional triamcinolone injections no augment the effects of endoscopic dilation in patients with corrosive esophageal strictures but were favourable in post surgical strictures.

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