Abstract

CASTANO LL, Rodrigo et al. Pólipos gástricos: Aspectos epidemiológicos y su relación con el consumo de bloqueadores de bomba. Rev Col Gastroenterol [online]. 2005, vol.20, n.4, pp.48-59. ISSN 0120-9957.

AIM. To analyze gastric polypoid lesions in our patient population with respect to histopathologic features and demographic, clinical, and endoscopic characteristics of patients and relation with proton pump blockers consumption. METHODS. Clinical records and histopathologic reports of patients with gastric polypoid lesions were analyzed retrospectively. Almost all lesions had been totally removed by either endoscopic polypectomy or biopsy forceps. Telephonically 117 patients were contacted to determine if there was or not consumption of proton pump blockers and the time of this consumption. RESULTS. One-hundred and fifty patients with gastric polypoid lesions were identified. There were 42 (28 %) men and 108 (72 %) women with a median age of 56 (range, 18 to 88) years. The most frequent presenting symptom was dyspepsia that was observed in 69 patients (46%). Symptoms were mostly related to various associated gastric abnormalities such as chronic gastritis or H pylori infection rather than polypoid lesion itself. Polypoid lesions were commonly located in the fundus (39%) followed by antrum (35%). Out of 150 patients, 69 (46 %) had the largest dimensions less than or equal to 5 mm and only 4 were pedunculated. The frequencies of hyperplastic polyps, inflammatory polyps, and fundic gland polyps were 55%, 18%, and 9% respectively. We also detected adenomatous polyps in 5 specimens, carcinoid tumor 5, GIST in 5, and other lesions in 12. Adenomatous changes were observed within six hyperplastic polyps. Histopathologic evaluation of the surrounding gastric mucosa demonstrated chronic gastritis in 131 (87 %) patients and H pylori infection in 87 (58 %). The average consumption of proton pump blockers was 6 months for the different histological variants except for carcinoid polyps that was 20 months. CONCLUSION. Hyperplastic polyps are the most frequently encountered subtype of gastric polypoid lesions. They are usually associated with chronic gastritis or H pylori gastritis. Contrary to the previous belief, they may harbour adenomatous changes or dysplastic foci. There was a trend in the relation between a major time of proton pump blockers consumption and the carcinoid polyp. Therefore, endoscopic polypectomy seems as a safe and fast procedure for both diagnosis and treatment of gastric polypoid lesions at the same session.

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