Revista Colombiana de Gastroenterologia
Print version ISSN 0120-9957
FORERO, Elías et al. Preparación intestinal para colonoscopia; comparación entre polietilenglicol y manitol: Estudio de costo efectividad, doble ciego aleatorizado. Rev Col Gastroenterol [online]. 2005, vol.20, n.4, pp. 60-71. ISSN 0120-9957.
OBJECTIVE. To compare the effectiveness, security and adherence of the manitol and polietilenglicol for the intestinal preparation of diagnostic colonoscopy. STUDY. Clinical Controlled Randomized Double Blind. SET. Unit of Gastroenterology of Central Hospital of the Police. PARTICIPANTS. 297 patients were included, 142 to the group A (polietilenglicol) and 155 to the group B (Manitol). INTERVENTION. Preparation with 4 liters of solution of Polietilenglicol in the group A, preparation with 500 ml of Manitol 20% and Bisacodilo 20 mgs in the Group B. MAIN MEASURED RESULTS. Qualitative and quantitative evaluation of the preparation quality in colon proximal and distal according to the Vanner scale, proportion of total colonoscopy, incidence of adverse events, and proportion of fellows that completed the protocols, effect on the levels séricos of sodium, potassium, chlorine and calcium. RESULTS. The groups were comparable in age and sex (p> 0,05), all the admitted fellows were included in the analysis: They was not difference in the groups when evaluating proportion of complete colonoscopia (A) 92.9%, (B) 90%, (IC 95% 0.96-1.09); excellent or good Preparation (A) 86.6%, (B) 91.6% (IC 95% 0.87-1.02); frequency of adverse events not serious (A) 20.5%, (B) 23.9% (IC 95% 0.56-1.31); They was not difference it has more than enough electrolytes serics. CONCLUSIONS. The intestinal preparation for diagnostic colonoscopy with manitol or polietilenglicol provides results of similar colonic cleaning, being sure, reliable and well tolerated medications, the manitol with a significantly smaller cost that of polietilenglicol constitutes it in the first election for diagnostic colonoscopy.
Keywords : Study controlled randomized; Colonoscopy; Manitol; Polietilenglicol.