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Revista colombiana de Gastroenterología

Print version ISSN 0120-9957On-line version ISSN 2500-7440


SIERRA ARANGO, Fernando. Rol of domperidone in the treatment of non-ulcer dyspepsia: A systematic review. Rev Col Gastroenterol [online]. 2006, vol.21, n.4, pp.261-266. ISSN 0120-9957.

The treatment of non-ulcer dyspepsia keeps on being a conundrum. In spite of the many treatments that we have to deal with this disease neither has shown a benefit much higher than the placebo. One of the most common types of medication to treat this disease is the proquinetics. Among this class of medications; domperidone which is a dopaminergic antagonist has shown a moderate effect. The porpoise of this systematic review is assessing the existent bibliography over the actual roll of domperidone in the treatment of patients with non-ulcer dyspepsia. After the critical appraisal of the literature that I have done; we can conclude that domperidona is safe and useful in the treatment of non-ulcer dyspepsia, in fact the number needed to treat is only 4.

Keywords : Non ulcer dyspepsia; proquinetics; Domperidona; number needed to treat.

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