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Revista Colombiana de Gastroenterologia

Print version ISSN 0120-9957

Abstract

RODRIGUEZ MARIA, Roberto; BAQUERO RODRIGUEZ, Hernán Eduardo  and  CRUZ GARRIDO, Eduardo Antonio. Gastrointestinal amyloidosis. Rev Col Gastroenterol [online]. 2008, vol.23, n.3, pp.266-275. ISSN 0120-9957.

The amyloidosis is a disease of unknown etiology, it is characterized for the deposit of amorphous substance (amyloide), in diverse organs and tissues extracell spaces determining functional an structural alterations according to the location and structural alterations according to the location and intensity of the deposit. About 75 % of the patients who suffer this disease have a primary amyloidosis, 5% of whole present suffer amyloidosis secondary, and less than the 5% develops a familiar amyloidosis. The clinical manifestations are not specifics, determinated for the organ or affected system. The diagnostic is based on the clinical suspicion and the proof of the amyloide substance on the tissues. It is really difficult to know the evolution of this disease because it is complicated to find the beginning of the same one. About the medical treatment they have observed favorable response with melfalan and prednisone. With regard to the organs transplant there is not protocol about universal acceptance it depends on every case, extension and evolutionary estate of the disease. Now will present an amyloidosis primary systemic case, where one finds an affected gastrointestinal system.

Keywords : Primary amyloidosis sistemic; secundary amyloidosis; renal failurie; Multiple myeloma; chronic diahrrea.

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