Abstract

HANI DE ARDILA, Albis. The pathogenesis of gastroesophageal reflux. Rev Col Gastroenterol [online]. 2009, vol.24, n.1, pp.87-94. ISSN 0120-9957.

The changes that have occurred in the last 20 years in the better understanding of everything associated with gastroesophageal reflux have been truly spectacular. This was achieved because the technological development has brought to our survey techniques that have enabled us to know very thoroughly, not only the physiology of the gastro-union, but also that of the esophagus. In this sense, the introduction of such methods now available to any hospital, such as esophageal manometry and pH, and in other cases a little more sophisticated like high-resolution manometry, have identified with great precision the behavior of the sphincter lower esophagus, as well as the finding of the presence of acid in the esophagus. Thus the pathogenesis of gastroesophageal reflux disease is considered a multifactorial disease, but gastroesophageal reflux is a physiological condition, in certain circumstances can become pathological, causing a digestive disorders in which individuals are forced to refer not only to the specialist but also to the general practitioner. Better understanding of the physiology believe leads to better diagnostic and therapeutic approach, this is the reason for this revision.

Keywords : Motility; protective factors; aggressor factors; Reflux.

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