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Revista Colombiana de Gastroenterologia

Print version ISSN 0120-9957


OSPINA NIETO, John  and  QUINTERO, Álvaro Pío. The Peutz-Jeghers's Syndrome. Rev Col Gastroenterol [online]. 2009, vol.24, n.2, pp.188-199. ISSN 0120-9957.

The Peutz-Jeghers's syndrome, it is a poliposis of low incident that characterizes for the combination of pigmented mucocutaneous and hamartoma polyps in the gastrointestinal tract. This is a dominant autosomic syndrome of changeable penetration and in a high percentage it is associates to mutations of the gene STK11/LKB1, located in the band 19p13.3. The clinical presentation changes from completely asymptomatic patient to, intestinal obstruction, high risk of gastrointestinal cancer and extra gastrointestinal neoplasm and of short intestine syndrome (for multiple resections). This syndrome is of symptomatic managing in the acute events and of periodic follow-up with polipectomy of the biggest polyps in order to avoid the transformation to neoplasm and of detecting the tumour early injuries. In the present article let’s sense beforehand two patients who entered to the Hospital Universitario de la Samaritana with intestinal obstruction and signs of acute abdomen needing intestinal resection and polipectomy surgical with report of pathology that showed hamartom polyps. The follow-up I realize in the Hospital Cardiovascular del niño de Cundinamarca with endoscopy, enteroscopy and periodic polipectomy. One presents in addition a review over this infrequent entity and the in force recommendations of follow-up.

Keywords : Peutz-Jeghers; Enteroscopy; polipectomy.

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