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Revista colombiana de Gastroenterología
Print version ISSN 0120-9957On-line version ISSN 2500-7440
Abstract
SUAREZ RAMOS, María del Pilar; MARTINEZ BAQUERO, Diana Lucía; CABARCAS SANTOYA, Martha Eugenia and RICAURTE GUERRERO, Orlando. Reactive gastropathy: Frequency in endoscopic biopsies evaluated at the Universidad Nacional de Colombia. Rev Col Gastroenterol [online]. 2011, vol.26, n.4, pp.253-260. ISSN 0120-9957.
Reactive gastropathy (RG) is primarily produced by non-steroid antiinflammatory drugs (NSAIDs) and bile reflux. It can occur alone or coexist with other types of chronic gastritis (CG). 5,079 histopathological reports of gastric biopsies from 4,254 patients were reviewed: 825 of them had 2 to 7 follow-up studies. 12.8% of these patients were diagnosed with GR while 63.4% were diagnosed with chronic non-atrophic gastritis (CNAG) and 27.3% were diagnosed with chronic multifocal atrophic gastritis (CMAG). Helicobacter pylori infections were found in 61.6% of the cases with CNAG, 51.5% with CMAG, and in 18.5% of cases with GR only (p <0.0001). Among patients suffering from both RG and CNAG 43.9% had H. pylori infections. 40.7% of those suffering from both CMAG and RG were infected with H. pylori. During monitoring of patients RG diagnoses increased to 22.2% in the second study, 26.7% in the third study, and 28.8% in the fourth through seventh studies. Histological findings of RG in these cases are probably residual following disappearance of inflammatory infiltrates due to treatment
Keywords : Reactive gastropathy; chronic gastritis; H. pylori; bile reflux; post gastrectomy status; non-steroid antiinflammatory drugs.