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Revista Colombiana de Gastroenterologia

Print version ISSN 0120-9957


MARIN, Juan Ignacio et al. Two Case Reports and a Literature Review of Liver Transplantation for Epithelioid Hemangioendothelioma. Rev Col Gastroenterol [online]. 2015, vol.30, n.2, pp.211-215. ISSN 0120-9957.

Hepatic epithelioid hemangioendothelioma is a rare, aggressive and unpredictable tumor. Its incidence is less than one case per million people per year. Most commonly, it occurs in young women who exhibit nonspecific symptoms such as abdominal pain and weight loss. Radiologically it presents as multiple bilateral and peripheral nodules or masses with retraction of the capsule of the liver. In some cases there is calcification and vascular compromise. A liver biopsy should be performed to confirm the diagnosis and to rule out alternative diagnoses such as angiosarcoma, hepatocellular carcinoma, cholangiocarcinoma and metastasis. Management depends on the extension at presentation, but only 10% of cases are amenable to resection. Although in recent decades liver transplantation has become a management option, only studies of isolated cases reported by various transplant centers around the world have been published so far. In this article, we report our experience with two patients who were diagnosed with hepatic epithelioid hemangioendothelioma in which there were no possibilities of resection. Diagnoses were histologically confirmed, and since the patients had no extra-hepatic compromises, liver transplantations were performed.  Both were successful and without recurrence at 4 and 6 years after transplantation

Keywords : Liver transplantation; hepatic epithelioid hemangioendothelioma; liver tumor.

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