Abstract

LOPEZ PANQUEVA, Rocío del Pilar. Malignant Hepatic Neoplasms: Hepatocellular carcinoma: the roles of liver biopsies and immunohistochemical studies and other important issues. Rev Col Gastroenterol [online]. 2015, vol.30, n.2, pp.232-242. ISSN 0120-9957.

We continue with our review of liver tumors in which we will refer to the most common primary malignant liver tumors. As mentioned previously, hepatobiliary malignancies are a spectrum of invasive tumors whose names depend on their origins. According to the International Agency for Research on Cancer (IARC), malignant liver tumors are the second leading cause of death worldwide with approximately 745,000 deaths/year. (1) As in the previous article, the aim here will be to identify the most relevant aspects of these neoplasms. In particular we will look at morphological findings that generate major diagnostic problems and at the usefulness of immunohistochemical studies and their differential diagnoses. Hepatic carcinoma, the most frequent malignant epithelial tumor of the liver is the focus of the first part of this review. We will look at some of its variants and its precursor lesions, and at the controversial role of liver biopsies for diagnosis

Keywords : Malignant liver tumors; hepatocellular carcinoma; dysplastic nodules; fibrolamellar hepatic carcinoma; percutaneous liver biopsy; aspiration biopsy; immunohistochemistry.

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