Abstract

PRIETO O, Jhon E et al. Clinical Characteristics and Decompensation in Patients with Liver Cirrhosis Treated at Two Hepatology Centers in Bogota DC from 2010 To 2014. Rev Col Gastroenterol [online]. 2016, vol.31, n.1, pp.1-8. ISSN 0120-9957.

Introduction: Cirrhosis is the final medical condition of various progressive liver disease. Its prevalence varies from one country to another. Currently alcohol abuse, non-alcoholic fatty liver disease and chronic viral hepatitis are mentioned as the main causes. In our centers we have no clinical studies regarding this disease. Materials and Methods: This is a retrospective, descriptive study of the clinical histories of patients who were diagnosed with liver cirrhosis between January 1, 2010 to March 31, 2014. Results: The study included 419 patients, 50.1% of whom were women and 49.9% of whom were men. The average age at diagnosis of cirrhosis 63 years. 73% of patients had physical findings of chronic liver disease and 27% had normal physical examinations. The main etiologies in this series were nonalcoholic steatohepatitis (25.5%), alcoholic cirrhosis (14.8%), hepatitis C infection (14.6%), autoimmune cirrhosis (10%), nonalcoholic steatohepatitis plus alcohol (6.7%),  and others (14.6%). The Child-Pugh classification could be calculated in 394 patients. Of these 59.1% were classified A, 32.4% were classified B, and 8.3% were classified C. The primary reasons for decompensation ascites (36.1%), bleeding varices (28.4%) and hepatocellular carcinoma (15.3%). Conclusions: Local epidemiological behavior does not differ from those found elsewhere in the  world. Attention needs to be paid to detection in early stages and NASH as the main etiological factor.

Keywords : Gastroenterology; liver cirrhosis; ascites; hepatitis non-alcoholic steatohepatitis (NASH).

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