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Revista Colombiana de Gastroenterologia

Print version ISSN 0120-9957


DUQUE JARAMILLO, Alejandra et al. Frequency of Antibodies to Hepatitis E In Blood Donors in the Municipality of Yarumal, Antioquia. Rev Col Gastroenterol [online]. 2016, vol.31, n.3, pp.229-234. ISSN 0120-9957.

Introduction: The hepatitis E virus (HEV) is transmitted via the fecal-oral route and causes acute liver disease. In Colombia there have been some studies of patients who have been diagnosed with viral hepatitis, of swine farm workers and in environmental samples. Objective: The objective of this study was evaluate samples from blood donors in the municipality of Yarumal in the department of Antioquia for the presence of anti-HEV antibodies. Methods: Serum samples were obtained from blood donated to the Colombian Red Cross by blood donors on a voluntary basis in a campaign in the municipality of Yarumal. Samples in the presence of anti-HEV IgM and IgG ELISA using commercial kit was determined.Results: Forty-two serum samples were analyzed: 19 (45.2%) were positive for anti-HEV IgG. None of the samples were positive for anti-HEV IgM. Conclusions: This is the first report of anti-HEV antibodies in blood donors in Colombia. The frequency of anti-HEV (45.2%) is higher than previously reported in other studies in this country and in blood donors in other Latin American countries. This frequency may be linked to contact with infected pigs and to exposure to water contaminated with the virus. However, additional studies should be conducted in similar populations in the country to confirm this finding

Keywords : Hepatitis E virus; antibodies; ELISA; blood donors; rural populations.

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