Abstract

PEREZ GUERRA, Verónica et al. Acute-On-Chronic Liver Failure. Rev Col Gastroenterol [online]. 2016, vol.31, n.3, pp.262-272. ISSN 0120-9957.

Acute-on-chronic liver failure (ACLF) includes acute deterioration of liver functions in patients with either chronic de novo liver disease or already diagnosed liver disease. ACLF can be triggered by various hepatic or extrahepatic precipitating factors. Among its clinical manifestations are renal dysfunction, hepatic encephalopathy, and multisystem organ failure. If not treated promptly translate the prognosis can be poor. Several scoring systems have been used to assess liver function and patient prognosis. Although multisystem organ failure contraindicates liver transplantation, it remains the treatment of choice for this patients

Keywords : Acute-on-chronic liver failure; MARS; hepatorenal syndrome; hepatic encephalopathy; multisystem organ failure; immune paralysis; SOFA scores.

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