Abstract

GALLO E, Simón; CARABALLO C, Cesar; OROZCO M, Mateo  and  MUNOZ, Octavio Germán. Current treatment and new therapies against chronic hepatitis B virus infection. Rev Col Gastroenterol [online]. 2017, vol.32, n.2, pp.131-140. ISSN 0120-9957.  https://doi.org/10.22516/25007440.138.

Chronic hepatitis B virus infections are a serious public health problem worldwide. Its consequences can be deadly, and current treatment offers only control of the disease rather than a cure. The main limiting factors for a cure are the difficulty of destroying the cDNA of the virus in the cell nucleus and the presence of viral genetic material integrated into the DNA of the host cell. Multiple fronts of research focus on finding a definitive cure by enhancing the immune response of the host or by acting directly against the virus and its replication cycle. This article presents the main advances that have been made in this field.

Keywords : Hepatitis B virus; Immunotherapy; Antiviral Agents; Chronic Hepatitis; Liver Cirrhosis.

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