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Revista Colombiana de Gastroenterologia

versão impressa ISSN 0120-9957


ARANGO M, Lázaro Antonio et al. Extra nodal follicular non-Hodgkin B lymphoma affecting the colon, on the basis of a case. Rev Col Gastroenterol [online]. 2018, vol.33, n.3, pp.292-296. ISSN 0120-9957.


Non-Hodgkin’s lymphoma (NHL) is a malignant disease that presents in an extranodal form. It affects the gastrointestinal tract in up to 50% of cases with the colon being the least frequently compromised portion. In the few cases in which it is affected, the cecum is most often compromised due to its large lymphoid content. The colon of the patient presented here was compromised by a mass in the cecum. Biopsies showed grade II follicular NHL with follicular and diffuse patterns. This histological type has the highest prevalence and has shown the best results with chemotherapy (R-CHOP scheme) alone and in conjunction with radiation therapy and occasionally with surgery. The patient received treatment followed by adequate evolution. Combination therapy has been shown to result in longer survival times, although there are studies which have reported good results with monotherapy as in this case.

Clinical Case:

The patient was a 38-year-old woman. A colonoscopy showed a tumor in the cecum. Its pathology was compatible with extra-follicular follicular NHL type B which was confirmed by immunohistochemistry. Imaging extension studies confirmed abdominal and thoracic adenopathies in conglomerates. The oncology department treated the patient with a chemotherapy with R-CHOP protocol with a good response.

Discussion and conclusions:

Since extranodal NHL rarely affects the colons, this case deserved to be reported. Management can be multidisciplinary, but the prognosis depends on individual characteristics in each case.

Palavras-chave : Non-Hodgkin’s lymphoma; extranodal involvement; colon malignancy.

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