Abstract

LIMAS-SOLANO, Luis Manuel; VARGAS-NINO, Carlos Ernesto; VALBUENA-RODRIGUEZ, Diana Carolina  and  RAMIREZ-LOPEZ, Laura Ximena. Fecal Microbial Transplantation: A Review. Rev Col Gastroenterol [online]. 2020, vol.35, n.3, pp.329-337.  Epub Mar 01, 2021. ISSN 0120-9957.  https://doi.org/10.22516/25007440.486.

Gut microbiota is defined as healthy when there are groups of microorganisms that enhance the host’s metabolism, confer resistance to infections, inflammatory processes, the development of malignancies or autoimmunity, promote endocrine functions and support neurological function through the so-called gut-brain axis. Fecal microbial transplantation is the transfer of fecal matter from a healthy donor into the gastrointestinal tract of another person, usually a patient with a specific pathology, to manipulate the composition of the recipient’s microbiota and contribute to the treatment of his or her condition. The concept of fecal microbial transplantation breaks with the traditional thought of bacteria as harmful elements and draws attention to what is probably the most undervalued of the human body’s excreta: feces. Its high efficiency has been demonstrated and the procedure is recognized by the many patients it has helped, which can already be counted in thousands. The objective of this literature review was to describe the basics of fecal microbial transplantation for the treatment of Clostridioides difficile infections.

Keywords : Dysbiosis; Fecal microbiota; Fecal microbial transplantation; Bacteriotherapy; Infectionn; Clostridium difficile.

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