Abstract

OTERO-REGINO, William; OTERO-PARRA, Lina  and  VEITIA, Guillermo. Pouchitis, a complication associated with the surgical treatment of ulcerative colitis. Diagnosis and treatment. Review. Rev. colomb. Gastroenterol. [online]. 2021, vol.36, n.1, pp.65-72.  Epub Oct 21, 2021. ISSN 0120-9957.  https://doi.org/10.22516/25007440.426.

Between 20 % and 30 % of patients with ulcerative colitis (UC) undergo surgery because it is not treatable or because it is associated with a fulminant course, dysplasia, or colon cancer. The surgery of choice is proctocolectomy with ileal-anal pouch. However, 20 %-50 % of patients present with pouchitis 10 years after surgery. The diagnosis is made based on clinical manifestations, endoscopic alterations, and histology. The drugs used in the treatment of UC are not as effective in pouchitis and the first-line treatment is antibiotics administration. Depending on the initial response and clinical course of the condition, subsequent treatment will be chosen. This review discusses the most important aspects of the epidemiology, diagnosis, pathogenesis, and treatment of pouchitis.

Keywords : Ulcerative colitis; Pouchitis; Antibiotics; Prophylaxis.

        · abstract in Spanish     · text in English | Spanish     · English ( pdf ) | Spanish ( pdf )