Resumen

VIERA-CONTRERAS, María José; CUELLO, Eduardo J.; OBANDO-GOMEZ, Evelin Johana  y  CUELLO-LACOUTURE, Eduardo. Beyond the Lauren Classification: An Uncommon Case of Mixed Gastric Adenocarcinoma. Rev. colomb. Gastroenterol. [online]. 2026, vol.41, n.1, pp.125-130.  Epub 28-Abr-2026. ISSN 0120-9957.  https://doi.org/10.22516/25007440.1426.

Gastric cancer (GC) is a heterogeneous neoplasm with high mortality, particularly in countries such as Colombia. Among its variants, mixed gastric adenocarcinoma-combining intestinal and diffuse components-represents an infrequent but clinically aggressive form (6%-22%). An atypical case is presented involving an apparently benign gastric polyp, whose histopathological examination revealed a poorly differentiated (grade 3) mixed adenocarcinoma, classified as Borrmann type I. Cases of this nature underscore the importance of meticulous endoscopic and histological evaluation, even in lesions with an innocuous appearance, and highlight the need for rigorous surveillance in neoplasms with aggressive biological behavior.

Palabras clave : Gastric neoplasms; adenocarcinoma; stomach neoplasms.

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