Resumo

RUBIO GUERRA, Alberto Francisco. From endothelial dysfunction to clinic. Medicas UIS [online]. 2013, vol.26, n.2, pp.51-57. ISSN 0121-0319.

Background: coronary heart disease is the main cause of death worldwide, and coronary atherosclerosis is responsible of about 90% of ischemic heart events . Objective: review the pathophysiology of atherosclerosis, from the factors that promote endothelial dysfunction, until the apparition of the diseases secondary to this disease. Conclusions: atherosclerosis is a chronic and complex process that begins during childhood, several mechanisms contributes to atherogenesis including endothelial dysfunction and inflammation. A better understanding of the pathogenesis of atherosclerosis will provide us with tools for reducing mortality resulting from coronary artery disease. (MÉD.UIS.2013;26(2):51-7)

Palavras-chave : Atherosclerosis; Inflammation; Risk.

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