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Medicas UIS

versão impressa ISSN 0121-0319

Resumo

GOMEZ, Sergio; ALVAREZ, Yelitza  e  PUERTO, Jorge Andrés. Miastenia Gravis: una visión actual de la enfermedadMyasthenia Gravis: a current vision of disease. Medicas UIS [online]. 2013, vol.26, n.3, pp.13-22. ISSN 0121-0319.

Introduction: myasthenia gravis is a neuromuscular autoimmune disease which affects the motor plate. Its prevalence is low, being higher in European countries and the United States. Few reviews have been published in Colombia and Latin America about this disease. Aim: submit a current and complete look of the disease worldwide and Colombia from its epidemiology, etiology, clinical diagnosis, treatment and all health staff and students should know about this disease. Methods: we performed a search in virtual libraries: Scopus, Google Scholar and Medline with keywords: myasthenia gravis, epidemiology, Colombia, treatment, etiology, diagnosis. Discussion: The main feature is the fluctuating muscle weakness, manifested as fatigue in striated skeletal muscle. There are several approaches to classify, depending on the age of onset, serological test results and clinically by Osserman classifications and the Myasthenia Gravis Foundation of America MGFA. Diagnostic methods are applied depending on the clinical manifestations, however, there is still no method with specificity of 100%. Treatment must be individualized based on the clinical characteristics of each patient and dependent on the stage of the disease Conclusion: Through improved knowledge of the disease, diagnosis and treatment, mortality has been reduced, as well as underdiagnosis, improving the quality of life of patients and their subsequent function. (MÉD UIS. 2013;26(3):13-22)

Palavras-chave : Myasthenia Gravis; Neuromuscular Diseases; Autoimmune Diseases.

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