SciELO - Scientific Electronic Library Online

 
vol.28 issue1Acute exacerbations by infectious agents in patients with structural lung diseaseRespiratory viral infections in pediatrics: generalities about physiopathogeny, diagnosis and clinical outcomes author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Medicas UIS

Print version ISSN 0121-0319

Abstract

HERRERA-GOMEZ, Ana. Adrenal hyperplasia congenital: beginning of developmental and sexual differentiation disorders. Medicas UIS [online]. 2015, vol.28, n.1, pp.125-132. ISSN 0121-0319.

Adrenal hyperplasia congenital is a genetic disease that develops from an enzyme deficiency secondary to alterations in protein synthesis. This deficit disturbs the pathways of adrenal metabolism, specifically occurring in the cortex of the gland, such as, the glucocorticoid, mineralocorticoid and the sex hormones metabolism. These molecular variations translated to the clinics are expressed in a variety of possible presentations, each depending of the enzyme that is affected, since electrolyte, metabolic, renal abnormalities or and gastrointestinal tract disturbances, but one of these is commonly for all presentation, the development and sexual differentiation disorders. Among the most severe forms of adrenal hyperplasia congenital alterations of the external sexual characters that basically translate into virilization of the genitals duringgestational development, as well as precocious puberty, amenorrhea, infertility observed, among other. MÉD.UIS. 2015;28(1):125-132

Keywords : Adrenal Hyperplasia congenital; Sexual Development; Genetics; Sex Differentiation; Sex Characteristics.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )