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Medicas UIS
versión impresa ISSN 0121-0319versión On-line ISSN 1794-5240
Resumen
SANABRIA LOZANO, Diego Felipe et al. Adverse effects at the cardiovascular and neurological level associated with the consumption of modafinil. Medicas UIS [online]. 2020, vol.33, n.1, pp.31-38. Epub 30-Abr-2020. ISSN 0121-0319. https://doi.org/10.18273/revmed.v33n1-2020004.
Introduction:
modafinil is a neurostimulant drug used mainly to promote wakefulness, attention and decrease fatigue in certain behaviors that cause excessive daytime sleepiness.
Objective:
identify in the scientific literature the neurological and cardiovascular adverse effects caused by the consumption of modafinil.
Materials and Methods:
bibliographic review of the articles found between the months of April and July of 2019 in the PUBMED, SCOPUS, DIALNET databases. 51 articles passed the methodological quality assessment and were included in the review.
Results:
the main adverse effects at the cardiovascular level were identified as Tako-Tsubo cardiomyopathy and polymorphic ventricular tachycardia, while at the neurological level it can generate insomnia and dystonia.
Conclusions:
the consumption of modafinil generates repercussions on cognitive and cardiovascular functions, so its long-term use in healthy people is not advisable. MÉD.UIS.2020;33(1):31-8.
Palabras clave : Ventricular tachycardia; Dystonia; Modafinil; Central nervous system stimulants; Sleep-wake disorders; Narcolepsy.
