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Medicas UIS

Print version ISSN 0121-0319On-line version ISSN 1794-5240


CIFUENTES CIFUENTES, Yolanda; ANGEL-MULLER, Edith  and  DIAZ MORENO, Rosa Cecilia. Congenital syphilis due to undiagnosed maternal neurosyphilis: case report. Medicas UIS [online]. 2020, vol.33, n.1, pp.73-80.  Epub Apr 30, 2020. ISSN 0121-0319.

In the world, there has been an increase in cases of syphilis, gestational syphilis and congenital syphilis. It’s presented the case of a newborn with congenital syphilis, son of a mother with latent syphilis of indeterminate duration (VDRL 1: 4 dilutions) diagnosed and treated at week 12 of gestation, HIV negative, with seronegative partner for syphilis; despite treatment with three doses of 2’400 000 U of benzathine penicillin, the VDRL titres remained unaltered on both the control of the 25th week of gestation and at the time of delivery. The mother, in the postpartum period, was diagnosed with neurosyphilis and was treated with crystalline penicillin for 14 days.

The newborn was diagnosed with congenital syphilis by presenting 1:4 VDRL dilutions, increased aminotransferases, hematuria and proteinuria; he was treated with crystalline penicillin for 10 days.

Useful measures should be promoted in the prevention of gestational syphilis such as barrier methods, knowledge of the disease and assistance to prenatal control. It is mandatory to identify and treat pregnant women with syphilis by serological screening for the disease in order to prevent congenital syphilis. Serological follow-up should be strict to verify the effectiveness of the treatment and to investigate pregnant women who do not modify the titres after treatment. MÉD.UIS.2020;33(1):73-80.

Keywords : Syphilis; Congenital. Neurosyphilis. Pregnancy. Treponema.

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