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Medicas UIS

Print version ISSN 0121-0319On-line version ISSN 1794-5240

Abstract

MARTINEZ ROSADO, Larry Luber  and  CARDONA-ARIAS, Jaiberth Antonio. Fungal infections in a public hospital of reference for the care of people with HIV/AIDS, Medellín 2013-2017. Medicas UIS [online]. 2020, vol.33, n.2, pp.17-24.  Epub Aug 30, 2020. ISSN 0121-0319.  https://doi.org/10.18273/revmed.v33n2-2020002.

Introduction:

Mycosis is a health problem of great importance due to its frequency, clinical severity and resistance to azoles. Some studies have reported mycosis about 10% in person with Human Immunodeficiency Virus, with multiple etiologies such as Pneumocysti jirovecci, candidiasis, cryptococcosis, histoplasmosis and aspergillosis.

Objective:

To estimate the frequency and to characterize the fungal infections in patients of a specialized hospital for the care of people with HIV in Medellín-Colombia, 2013-2017.

Methods:

Descriptive observational cross-sectional study with 200 patients attended at the Hospital La María in Medellín. Secondary information source with sociodemographic and microbiological variables was used; analyzes included frequencies, confidence intervals for proportions and chi square test to compare the frequency of infection according to sex and age group, in SPSS 25.0.

Results:

The average age was 45.5 ± 17.3 and 66% were men. The overall frequency of fungal infections was 12.5% (CI 95% = 7.67-17.33), without statistical differences according to sex and age group. The prevalence of Candida spp. was 5.5% (CI 95% = 0.09-8.91), Histoplasma capsulatum and Cryptocuccus spp. 1.5% (CI 95% = 0.31-4.32) and Aspergillus fumigatus 0.5% (CI 95% = 0.01-2.75).

Conclusion:

We found a high frequency of fungal infections in the study population, with predominance of Candida albicans, this is a relevant finding to improve the surveillance of this type of infections in reference hospitals for the care of people with HIV/AIDS and establish baselines for further studies. MÉD.UIS. 2020;33(2):17-24

Keywords : Acquired Immunodeficiency Syndrome; HIV; Immunosuppression; Mycoses; Opportunistic Infections; Public Health Surveillance.

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