Abstract

MOGOLLON GALLO, Jesús Daniel et al. Disseminated intravascular coagulation. Medicas UIS [online]. 2020, vol.33, n.2, pp.75-84.  Epub Aug 30, 2020. ISSN 0121-0319.  https://doi.org/10.18273/revmed.v33n2-2020008.

Disseminated Intravascular Coagulation is an altered state of coagulation secondary to local or systemic inflammatory symptoms. It is characterized by increased coagulation and inadequate endogenous fibrinolysis resulting in intravascular fibrin formation, multi-organ microvascular thrombosis, and excessive consumption of blood coagulation factors, this triggers severe bleeding and thrombosis, which lead to organic and circulatory failure as the main clinical manifestation.This article aims to review the state of the art describing its definition, etiology, pathophysiology, clinical manifestations and news in its diagnosis and treatment. Accordingly, a bibliographic search was carried out in PubMed using the MeSH term “Disseminated Intravascular Coagulation”, selecting 63 articles for the relevance and pertinence of their information to the objective of the investigation. Therefore, it is expected to provide the clinician with the necessary tools to adequately respond to this pathology. MÉD.UIS.2020;33(2):75-84.

Keywords : Disseminated Intravascular Coagulation; Thrombin; Fibrinolysis; Hemorrhage; Thrombosis.

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