Abstract

GONZALEZ-CLAVIJO, Angélica María; BUITRAGO-BERMEO, Andrés Felipe  and  CARDENAS-MESA, Juan Diego. Primary hyperaldosteronism, a common pathology and underdiagnosed: presentation of a case. Medicas UIS [online]. 2024, vol.37, n.1, pp.25-31.  Epub Mar 30, 2024. ISSN 0121-0319.  https://doi.org/10.18273/revmed.v37n1-2024002.

Primary hyperaldosteronism is a poorly recognized but prevalent syndrome, characterized by the autonomous and independent production of aldosterone, which contributes to the genesis of arterial hypertension and cardiovascular diseases. A case of a 57-year-old woman diagnosed with arterial hypertension for 12 years is presented, treated with three antihypertensive drugs without achieving objectives and encountering hypokalemia during an episode of hypertensive emergency. Only after this event are studies indicated for primary hyperaldosteronism, which allow confirmation of bilateral secretion of aldosterone through selective adrenal vein catheterization, with excellent response to management with spironolactone. The lack of knowledge of primary care physicians about how to suspect and initiate the approach to this pathology has led to less than 1 % of real cases being diagnosed. With this case we pretend to socialize the diagnostic and therapeutic approach to this pathology.

Keywords : Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Hypokalemia; Renin-Angiotensin System.

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