Abstract

MANTILLA-HERNANDEZ, Julio Cesar; VILLADA-MURILLO, María Fernanda  and  MENDOZA-MOGOLLON, Elizabeth Teresa. Pathological analysis in an immunosuppressed patient with mucormycosis: a case report. Medicas UIS [online]. 2024, vol.37, n.1, pp.87-93.  Epub Mar 30, 2024. ISSN 0121-0319.  https://doi.org/10.18273/revmed.v37n1-2024007.

Mucormycosis is an acute infection caused by mucoralean fungi, manifesting in immunocompromised patients and often underdiagnosed in medical settings, impacting management and increasing mortality due to its low prevalence. The case of a 39-year-old man with HIV/AIDS and non-adherence to antiretroviral treatment is presented. He developed fever and cough for 21 days before hospitalization due to severe pancytopenia and wheezing. Despite antituberculous and broad-spectrum antimicrobial therapy, the patient experienced neurological deterioration, prompting the initiation of unsuccessful amphotericin B treatment. The patient succumbed, leading to a request for a medical-scientific autopsy. Autopsy findings revealed disseminated mucormycosis, possibly secondary to late-stage AIDS, emphasizing the importance of considering this infection in immunocompromised patients with atypical presentations. This case underscores the need for an early and specific clinical approach to improve outcomes in critical mucormycosis situations.

Keywords : Mucormycosis; Zygomycosis; Mucoral; Immunosuppression; Immunocompromised host; Acquired immunodeficiency syndrome.

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