SciELO - Scientific Electronic Library Online

 
vol.15 issue2ASSESSMENT OF THE BEHAVIOR CHARACTERISTICS OF MEDICAMENT PRESCRIPTION AT THE HEALTH CARE INSTITUTION, UNIVERSITY OF ANTIOQUIA, MEDELLÍN-COLOMBIAQUALITY OF LIFE AND QUALITY OF LIFE RELATED HEALTH author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Iatreia

Print version ISSN 0121-0793

Abstract

MUNETON PENA, CARLOS MARIO  and  RAMIREZ CASTRO, JOSÉ LUIS. CYTOGENETICS OF SOLID TUMORS. Iatreia [online]. 2002, vol.15, n.2, pp.86-95. ISSN 0121-0793.

CYTOGENETIC ANALYSIS OF TUMORS has provided valuable information on the biology of cancer. It has been established that more than half of solid tumors show chromosomal anomalies; therefore, cytogenetic analysis is of great usefulness for diagnostic and prognostic purposes. Identification of recurrent chromosomal anomalies in numerous tumors has been considered as an indicador of clinical importance. Cytogenetic studies in tissue tumors have revealed near 100,000 clonal chromosome abnormalities belonging to more that 30,000 human neoplasms. However, due to technical difficulties in cell cultures, only one third of solid tumors have been cytogenetically characterized. Conventional cytogenetics has been very useful for molecular characterization of new oncogenes and tumor-suppressor genes involved in human tumorigenesis. In this review, some important issues related with tumors of chromosomal etiology, the diverse types of chromosomal anomalies with their frequencies, modern diagnostic techniques as well as their impact on the diagnosis and prognosis of cancer are presented.

Keywords : ALTERACIONES CROMOSÓMICAS; CITOGENÉTICA; TUMORES SÓLIDOS; CARIOTIPO; CÁNCER.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )