Abstract

RAMIREZ GOMEZ, Luis Alberto; VASQUEZ DUQUE, Gloria María  and  MUNOZ MAYA, Octavio Germán. Rheumatologic manifestations of inflammatory bowel disease. Iatreia [online]. 2006, vol.19, n.3, pp.272-285. ISSN 0121-0793.

THE MAIN FEATURE OF INFLAMMATORY BOWEL DISEASE (IBD) is the continuous activation of the mucosa-associated immune system; the disease has two major forms of presentation: ulcerative colitis and Crohn's disease. The extraintestinal manifestations are present in 36% of patients, and any organ can be affected. There is an imbalance between proinflammatory and antinflammatory cytokines leading to a systemic disease. The rheumatologic manifestations of the IBD are: Peripheral arthritis, spondyloarthropathy and a third category that includes dermic and ocular lesions as well as metabolic bone disease. Control of the extraintestinal manifestations is based on systemic therapy with steroids, 5-ASA derivatives and biological anti-TNF therapy.

Keywords : EXTRAINTESTINAL MANIFESTATIONS; INFLAMMATORY BOWEL DISEASE; PERIPHERAL ARTHRITIS; SPONDYLOARTHROPATHY.

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