Print version ISSN 0121-0793
TAMAYO PEREZ, MARÍA EULALIA; ARANGO RIVERA, MARÍA VICTORIA and TAMAYO MUNERA, CAROLINA. Pathophysiology and risk factors of necrotizing enterocolitis in newborns less than 1.500 g. Iatreia [online]. 2006, vol.19, n.4, pp. 356-367. ISSN 0121-0793.
The Necrotizing enterocolitis (NEC) is a serious illness of the newborn that affects mainly the preterm infant. It corresponds to a diffuse intestinal necrosis with more affection of the ileocecal region. The pathophysiology is complex and multiple risk factors can cause the illness in a susceptible infant. Among the different theories about their appearance is observed that prematurity, intestinal isquemia, bacterial colonization and enteral feeding are the main risk factors, which can be favored by prenatal, perinatal or postnatal conditions. The aim of this article is to review the pathophysiology and the risk factors described in the current evidence.
Keywords : ENTEROCOLITIS; NECROTIZING; PRETERM INFANT; RISK FACTORS.