Abstract

GOMEZ JIMENEZ, Jorge Mario  and  ARIAS RESTREPO, Luis Fernando. Pregnancy and glomerulonephritis: A review. Iatreia [online]. 2008, vol.21, n.2, pp.140-152. ISSN 0121-0793.

Antecedent: Glomerulal involvement is rare during pregnancy, but the associated morbidity is serious and potentially lethal. How does it affect prognosis? Objective: To define guidelines for the care of women affected by glomerulal disease during the pregestational stage, gestation and puerperium, and the indications for dialysis and renal biopsy. Materials and methods: Analysis of textual revisions published between 1980 and 1992, and the publications of Medline between 1993 and 2007 (Pregnancy and Glomerulonephritis). Results: Few randomized controlled studies were found. Most studies were cross-sectional and cases series, but they allow the assertion that glomerulonephritis adversely affects gestational outcomes and that pregnancy favors renal damage and the lupus flare. Conclusion: The incidence of exacerbation of glomerulonephritis is higher during pregnancy and the perinatal and maternal outcomes are affected, especially in the presence of preeclampsia or antiphospholipid syndrome.

Keywords : Dialysis; Glomerulonephritis; Pregnancy; Renal biopsy; Renal failure; Segmental focal sclerosis.

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