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Iatreia
versão impressa ISSN 0121-0793
Resumo
ARENAS GOMEZ, Claudia Marcela; MERIZALDE SOTO, Gabriel Jaime e RESTREPO MUNERA, Luz Marina. Skin substitutes developed by tissue engineering. Iatreia [online]. 2012, vol.25, n.1, pp.5-11. ISSN 0121-0793.
The skin is a complex tissue vulnerable to different processes that may alter its structure, integrity and functionality, among them: burns, chronic wounds and various congenital diseases. Technological advances in biomaterials manufacture and cell culture have allowed the production of skin substitutes thus providing an alternative therapy for some of these complications. This review aims to update the general aspects, composition, future prospects and implementation of the most common skin substitutes currently available in the international market. Some experiences of the Tissue Engineering and Cellular Therapy Group (GITTC), at the University of Antioquia, Faculty of Medicine, in Medellín, Colombia, are also presented.
Palavras-chave : Allogeneic Cells; Autologous Cells; Biomaterials; Skin Substitutes; Tissue Engineering; Xenogeneic Cells.