SciELO - Scientific Electronic Library Online

 
vol.26 número4Heart disease characteristics in patients with systemic lupus erythematosusQuality of life in Dermatology: tests for its evaluation índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google

Compartilhar


Iatreia

versão impressa ISSN 0121-0793

Resumo

LONDONO AGUDELO, Jéssica María; NINO PULIDO, César Daniel; HOYOS VANEGAS, Natalia Andrea  e  JAIMES BARRAGAN, Fabián Alberto. Use of biomarkers for diagnosis and treatment of sepsis. Iatreia [online]. 2013, vol.26, n.4, pp.457-466. ISSN 0121-0793.

Background: Sepsis is a very complex clinical phenomenon in both its definition and pathophysiology. So far its diagnosis has been based only on clinical symptoms and signs together with the results of some laboratory tests. However, efforts are being done to find biomarkers that are able to identify sepsis or rule it out, and to serve as guide for treatment. Objective: This review describes the most thoroughly studied biomarkers of sepsis and their potential use, as well as the experience achieved in Medellín, Colombia, with research in this field. Methods: A search on this subject matter was carried out in PubMed, and a critical analysis was done of the most relevant papers found including those published in Colombia. Results and conclusions: More than 180 biomarkers have been studied, most of them for diagnostic and prognostic purposes. Unfortunately, none of them has exhibited the sensitivity and specificity required to be recommended for routine clinical practice. So far, procalcitonin has been the most promising biomarker. Doubtless, this line of research should be continued and reinforced.

Palavras-chave : Diagnosis; Prognosis; Sepsis; Septic Shock.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )