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Iatreia

Print version ISSN 0121-0793

Abstract

NIETO RIOS, John Fredy; BRAND, Sandra Milena; SERNA HIGUITA, Lina María  and  ARIAS, Luis Fernando. The collapsing variant of focal segmental glomerulosclerosis in children. Iatreia [online]. 2013, vol.26, n.4, pp.481-486. ISSN 0121-0793.

The collapsing variant of focal segmental glomerulosclerosis (FSGS) is a renal injury that may be idiopathic or associated with various factors; it is characterized by glomerular collapse, which leads to steroid-resistant nephrotic syndrome (NS) and progressive chronic renal failure. FSGS has not been well studied in children, in which most of the cases are idiopathic. We report six cases of the collapsing variant of FSGS in HIV-negative children who were resistant to immunosuppressive treatment. Three of the children died.

Keywords : Chronic Renal Failure; Focal Segmental Glomerulosclerosis; Nephrotic Syndrome.

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