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Print version ISSN 0121-0793


LOPEZ-TORRES, Vanessa; RAMIREZ-CHEYNE, Julián Andrés; LOZANO-CRUZ, Edgar  and  SALAMANCA-LIBREROS, Omar Fernando. Phacolytic uveitis associated with spontaneous rupture of anterior capsule in a patient with Alport syndrome. Iatreia [online]. 2019, vol.32, n.2, pp.133-140. ISSN 0121-0793.

Alport syndrome is a rare genetic disorder due to mutations involving the coding genes for type IV collagen characterized by renal failure, sensorineural hearing loss and ocular abnormalities. This article presents a 24-year-old man with one day of sudden decrease in visual acuity in left eye due to spontaneous rupture of anterior lens capsule, related to cataract, phacolytic uveitis and ocular hypertension. In the anamnesis, personal history of hearing loss, renal failure and two-family members with a clinical diagnosis of Alport syndrome were found. The inheritance map was suggestive of a dominant inheritance X-linked pattern. Topical treatment was initiated with prednisone, atropine and brimonidine/timolol. Subsequently, phacoemulsification and aspiration of lens residues was performed, obtaining clinical relief.

Keywords : Cataract; Lens Capsule; Nephritis, Hereditary; Uveitis.

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