Abstract

SOSA AVILA, Luis Miguel; MACHUCA PEREZ, Mayra Alejandra; SOSA AVILA, Carlos Arturo  and  GONZALEZ RUGELES, Clara Isabel. Methicillin-resistant Staphylococcus aureus infections in children in Bucaramanga Colombia. Rev. Univ. Ind. Santander. Salud [online]. 2010, vol.42, n.3, pp.248-255. ISSN 0121-0807.

Introduction: The emergence of the infection by community-acquired methicillin-resistant S. aureus, in children, is a public health problem in many countries of the world, however, in Colombia, local dates about the clinical features, risk factors and molecular characteristic are scarce. Materials and methods: This descriptive study compared the clinical and epidemiological behavior of infections by methicillin-resistant S. aureus and methicillin suceptible S. aureus. The gen mecA and lukS-PV y lukF-PV were detected by amplification and antibiotic sensitivity was determinated. Results: From January 2008 to June de 2009, 39 infections caused by S. aureus were diagnosed, 60% by methicillin-resistant S. aureus. In the group methicillin-resistant, there were more proportion of infants and previous use of antibiotics. The most frequents location of the infection were: Osteoarticular (54%) and Skin and soft tissue (41%). The gen mecA and lukS-PV y lukF-PV were detected in 93% and 86% of the methicillin-resistant S. aureus. Soft tissue abscess, an inflammatory response enhanced and sensitivity to the most of the antibiotics were most frequent in the group methicillin-resistant and Panton-Valentine leuokocidin (PVL) positive. Conclusions: We report the presence of infections by MRSA - AC, PVL + and sensitivity to the most of antibiotics, in our media. The most frequent features are the presence of soft tissue abscesses and an inflammatory response enhanced. Salud UIS 2010; 42: 248-255

Keywords : Methicillin-resistant Staphylococcus aureus; child; community-acquired infections.

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