Abstract

MANTILLA, Julio Cesar; BUITRAGO, Carlos Andrés; AROCHA, Jeshar  and  PRADILLA, Gustavo. Clinicopathological correlation in inmunocompetent patients with tuberculous meningitis, autopsy cases report in the Hospital Universitario de Santander-Colombia.. Rev. Univ. Ind. Santander. Salud [online]. 2012, vol.44, n.1, pp.57-66. ISSN 0121-0807.

Introduction: to describe three fatal cases of tuberculous meningitis and to establish clinical pathological correlation. Materials and methods: Revision of autopsy protocols between 01 january and june 30 of 2010 in the Department of Pathology of the Industrial University of Santander (UIS). Between 121 protocols of autopsies were 3 cases of tuberculous meningitis, of which clinical histories, histopathological slides and photographies were rewieved. Results: three cases of adults with age average of 39 years, without inmunosupresión with tuberculous meningitis. The clinical manifestations were migraine, vomit, fever, disartria, commitment of cranial nerves, motor alterations and disorders of consciousness. Conclusions: the tuberculous meningitis is the most serious form of the disease, with fatal course in nondiagnosed cases. The low index of suspicion and the similarity with other infections of the central nervous system, do not allow early diagnostic and nor opportune treatment. Salud UIS 2012; 44 (1): 57-66

Keywords : Tuberculosis; meningitis; central nervous system; tuberculous meningitis.