SciELO - Scientific Electronic Library Online

 
vol.50 número3Percepción de los estudiantes de los programas de Química Farmacéutica, Tecnología en Regencia de Farmacia y Medicina de la Universidad de Antioquia frente al uso terapéutico de los cannabinoidesAbordaje de los síntomas neurológicos desde la perspectiva de los cuidados paliativos índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Revista de la Universidad Industrial de Santander. Salud

versión impresa ISSN 0121-0807

Resumen

TORRADO G, Laura M; RINCON-OROZCO, Bladimiro  y  MARTINEZ-VEGA, Ruth A. Genotypification of Human Papilloma Virus in women of the comuna Norte de Bucaramanga. Rev. Univ. Ind. Santander. Salud [online]. 2018, vol.50, n.3, pp.225-232. ISSN 0121-0807.  http://dx.doi.org/10.18273/revsal.v50n3-2018007.

Introduction:

Persistent infection with high-risk Human Papilloma Virus is a necessary cause for the appearance of cervical cancer.

Objective:

Molecularly characterize circulating genotypes of Human Papilloma Virus in population of the north of Bucaramanga.

Methods:

Cross-sectional study in women aged from 35 to 65 years with risk ≥3 points for develop cervical cancer determined by a standardized survey. In a cervico-vaginal self-sampling probe a molecular test was performed by HPV Direct Flow CHIP technology.

Results:

810 women were interviewed, of these 435 (53.7%) performed self-sampling due to the risk calculated. The median age was 47.3 years (RIQ 41-53 years). Almost the entire population resides in poor conditions (stratum1 and 2) (98.8%) and most of them are from the Colombian subsidized social security system (87.2%). The prevalence was 10.6% (CI 95%: 7.8 - 13.8), for high risk genotypes it was 3.9% (CI 95%: 2.3 - 6.2), low risk of 3.5% (CI 95%: 1.4 - 5.6) and for indeterminate genotype of 1.9%. HPV-59 was the most common high-risk genotype and HPV-62/81 was a low-risk genotype. There was coinfection with high risk / low risk genotypes in five women and coinfection with two low risk genotypes in a woman.

Conclusion:

The prevalence of infection by Human Papilloma Virus in women living in vulnerable areas of Bucaramanga is lower than that reported in Bogotá and Cali (14.9% and 13%, respectively). No predominance of any particular high-risk genotype was found.

Palabras clave : Uterine cervical neoplasms; molecular diagnostic techniques; Human Papillomavirus DNA Tests; early detection of cancer; cross sectional analysis.

        · resumen en Español     · texto en Español     · Español ( pdf )