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Revista de la Universidad Industrial de Santander. Salud

Print version ISSN 0121-0807


OSORIO-PINZON, Johanna et al. Hormonal, metabolic and hematological profile in adults with the Human Immunodeficiency Virus. Rev. Univ. Ind. Santander. Salud [online]. 2018, vol.50, n.4, pp.296-306. ISSN 0121-0807.


Data on the impact of human immunodeficiency virus (HIV) infection on a hormonal, metabolic and haematological level in patients hospitalized in Colombia are scarce.


To describe the hormonal, metabolic and haematological profile of HIV patients hospitalized in a third level institution.

Material and method:

Cross-sectional observational study, which included sociodemographic, clinical, hormonal, metabolic and hematological variables of patients with HIV between 2013 and 2014.


We included 52 patients, 34 men, with an average age of 40 years (SD 12.6, Min: 21 Max: 79). 23% had tuberculosis, 13% had cerebral toxoplasmosis. 26 patients had a history of toxic consumption: cigarette (58%), alcohol (27%) and hallucinogenic substances (15%). 14% of the patients received antiretroviral therapy at admission, mainly with protease inhibitors. Other medications used were: trimethoprim-sulfamethoxazole (27.2%) and antituberculous drugs (15%). The main causes of hospitalization were cerebral toxoplasmosis (31%) and tuberculosis (15%). 52% of the population had Wasting syndrome. The time of diagnosis of HIV was <1 year in 48% of the population. 79% of the patients had a CD4 count <200 cell/mm3 (SD 199, Min: 3 Max: 641). In the hormonal profile, 58% (29 patients) presented alteration of the thyroid axis, of which 14 session profile of central hypothyroidism. 55.8% of men had hyperprolactinemia. The metabolic profile was characterized by hypertriglyceridemia (44%) and low HDL (81%). The most frequent electrolyte alteration was hyponatremia (37%).


In the population of patients hospitalized with HIV, endocrine alterations were found suggesting primary glandular, pituitary and adrenal involvement, with lipid and electrolyte alterations largely related to advanced disease.

Keywords : Human Immunodeficiency Virus; hormones; metabolic; hospitalization; Colombia.

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