Abstract

GOMEZ-CAMPONOVO, Mariana  and  FERNANDEZ, Grisel. Evidence of Food Safety in Relation to Cry Proteins in Genetically Modified Foods. Rev. Univ. Ind. Santander. Salud [online]. 2020, vol.52, n.4, pp.440-449.  Epub Sep 30, 2020. ISSN 0121-0807.  https://doi.org/10.18273/revsal.v52n4-2020011.

Developments in applying biotechnology to crops have generated strong ethical and social debates about its use. This study was aimed at reviewing epidemiological evidence regarding the consumption of genetically modified foods and the possible effects on human health, particularly certain insect-resistant crops in which isolated Bacillum thurigiensis Cry protein has been introduced. An in-depth review of databases was conducted for 2007-2019. Articles not referring to human health were excluded. In total, 1,350 were obtained and 118 were reviewed. As a result, it can be concluded that most studies have focused on chemical composition and in vitro or laboratory animal trials. Furthermore, the guiding principle of substantial equivalency, generally used today to evaluate potential health effects, should not replace rigorously evaluating products with nutritional, immunological, and toxicological trials. Lastly, this review demonstrates a lack of epidemiological evidence, and therefore, the safety of these foods cannot be conclusively determined based on evidence.

Keywords : Transgenic food; Genetically modified organisms; GMO; Food safety; Bt toxins.

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