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Revista de la Universidad Industrial de Santander. Salud
versão impressa ISSN 0121-0807versão On-line ISSN 2145-8464
Resumo
PENA-LOPEZ, Brigitte O.; ROMERO-BOHORQUEZ, Arnold R. e RINCON-OROZCO, Bladimiro. Importance of type I interferons in the antiviral immune response against the Human Papillomavirus. Rev. Univ. Ind. Santander. Salud [online]. 2021, vol.53, e503. Epub 14-Mar-2022. ISSN 0121-0807. https://doi.org/10.18273/saluduis.53.e:21034.
The interferons (IFNs) are very important cytokines in the interface between innate and adaptive immunity of the host, the role type I IFNs in the control of HPV is pivotal for an efficient immune response, so a wide knowledge about this topic will contribute understanding HPV pathogenicity mechanism. This review focuses on the HPV evasion mechanisms for the type I IFNs which are necessary for a malignant lesion development, otherwise develops knowledge about the type I IFNs functions on the HPV infection.
Palavras-chave : HPV; Uterine Cervical Neoplasms; Interferons Type I; Immune System.