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Revista de Ciencias

Print version ISSN 0121-1935

Abstract

PADILLA QUINTERO, Beatriz Cristina et al. Preparation and Characterization of Chitosan Based Gels for Possible Biomedical Applications. rev. cienc. [online]. 2017, vol.21, n.1, pp.91-99. ISSN 0121-1935.  http://dx.doi.org/10.25100/rc.v21i1.6349.

The polymeric gels have a wide range of biomedical applications including their use for tissue growth, controlled drug release, enzyme immobilization, among others. Due to the ability of the gels to store water inside and the ionic conductivity that could be generated through ionizable functional groups, these materials may have applications in clinical diagnosis and in electro-therapy. In the present research, conductive gels based on chitosan (a biodegradable and biocompatible polymer) were prepared using glutaraldehyde as crosslinking agent. Chitosan gels were characterized by infrared spectroscopy with Fourier transform (FTIR) and it was also determined the values for their viscosity (μ), electric conductivity (κ) and pH. These properties vary as the crosslinking degree changed. One of the samples with comparable values to those of the commercial gels presented an absolute viscosity of 365x103 cP, ionic conductivity of 0.2140 Sm-1 and pH of 3.5, which are promising values for their use in commercial gels with biomedical applications.

Keywords : conductive gels; chitosan; biomaterials.

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