Resumen

CORREDOR-SANTAMARIA, Wilson et al. Induction of micronuclei and other nuclear abnormalities in Astyanax gr. bimaculatus (Pisces: Characidae) exposed to phenanthrene. Orinoquia [online]. 2012, vol.16, suppl.1, pp.237-247. ISSN 0121-3709.

Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) associated with the oil industry, highly lipophilic, ubiquitous and with the property to persist in the environment for longer periods. Despite its impact, few studies has been carry out in tropical fish evaluating the PAH effect, therefore, the aim of this study was to determine the presence of micronucleus and other nuclear abnormalities in peripheral blood erythrocytes in Astyanax gr. bimaculatus exposed to phenantrene. Fish (n=9) were injected intraperitoneally with 0.1, 1 and 10 µg/g BW of phenantrene solution. Cicliphosphamide and vegetable oil were used as a positive and negative control, respectively. Peripheral blood samples were collected at 0 and 96 hours. At 96 h exposure, the two higher phenantrene concentrations showed genotoxic effect on Astyanax gr. bimaculatus erythrocytes caused by the micronucleus induction and other nuclear morphological alterations. These results suggest that Astyanax gr. bimaculatus, a native freshwater fish, has a great potential as a bioindicator of polycyclic aromatic hydrocarbons genotoxicity.

Palabras clave : Chromosomal aberration; bioassays; genotoxic; polycyclic aromatic hydrocarbons; toxicity.

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